From Toronto:

Follow Q.E.W. exit 38B Highway 55. Follow the signs to Niagara-on-the-Lake. Follow Hwy 55(Niagara Stone Rd) for approx. 13km (8 miles). On entering the Historic town of Niagara-on-the-Lake, just past Jackson Triggs Winery, Hwy 55 becomes Mississauga St. - Go through the set of lights (Mary St.) past Tim Hortons and turn left on Gage St.

From the USA: Enter Canada at the Lewiston Bridge onto Hwy 405. After about 2 miles take Stanley Rd exit. Follow the signs to Niagara-on-the-Lake along Portage Rd. to the traffic circle and along the Niagara Parkway. Continue through the Heritage District of Niagara-on-the-Lake and, at the Golf Course, turn left on Mississauga St (Hwy 55) turn right onto Gage Street.